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All the analyses performed in our study were based on de-identified publically available data, and they were performed in compliance to the Helsinki declaration. National Center for Biotechnology InformationU. Duke scandal highlights need for genomics research criteria. Lawson Health Research Institute View all latest news releases. Background Currently, a number of molecular-based prognostic and predictive tests for breast cancer are offered as laboratory services for clinical use [ 12 ]. Our study provides a prototypic example for reproducible development of computational algorithms for learning prognostic biomarkers in the era of personalized medicine. J Biol Chem. A 2-gene classifier for predicting response to the farnesyltransferase inhibitor tipifarnib in acute myeloid leukemia.
Luigi Marchionni Google Scholar Citations
Luigi Marchionni is Associate Professor of Oncology at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, USA. In the past, Dr.
Marchionni major research activities focused on DNA sequences annotation, and the development of novel methods for gene expression profiling. I am an Associate Professor of Oncology at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD.
Luigi Marchionni VC Daniel, L Marchionni, JS Hierman, JT Rhodes, WL Devereux.
C Tomasetti, L Marchionni, MA Nowak, G Parmigiani, B Vogelstein.
A relative small fraction of published cancer prognostic markers have subsequently been introduced in clinical practice, despite the large number of available studies focusing on biomarkers development. National Center for Biotechnology InformationU. This finding probably indicates that the additional features of the gene signature not used in the 8-TSP classifier might carry additional prognostic information beyond five years see Additional files 1 and 2.
New computational strategy designed for more personalized cancer treatment ScienceDaily
Consequently, we performed a re-analysis of MammaPrint data. Competing interests The authors declare that they have no competing interests.
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Nicole Pagane, Anching Lien, Tejasvi Matam, Elana J. Fertig, Nathan D.
Faculty/postdoc job opportunities in genomics across Johns Hopkins · Simply Statistics
Price, Laurent Younes, Luigi Marchionni, and Donald Geman. While they work in some patients, they don't work in the vast Ranee Mehra, Sridhar Nimmagadda, Luigi Marchionni, David Sidransky, Ivan.
Tiny GPS backpacks uncover the secret life of desert bats University of Helsinki Could biological clocks in plants set the time for crop spraying?
Biological functions of the genes in the mammaprint breast cancer profile reflect the hallmarks of cancer. Top Scoring Pair. Disclose all data in publications.
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Each of the 8 gene pairs votes independently; patients with two or more votes are classified as poor prognosis.